Cytokines A-F
Cytokines G-L
Cytokines M-Z
ATK - Family of serine/threonine kinases
CCL1 (I309, TCA3) - Expressed by endothelial cells, monocytes, and other lymphocytes
CCL11 (EOTAXIN) - Pro-inflamitory and imunomodulatory
CCL2 (MCP-1, JE) - Chemoattracts monocytes and macrophages, pro-inflamitory
CCL3 (MIP-1a) - Macrophage inflamitory protein, induces IL6 production
CCL4 (MIP-1b) - Macrophage inflamitory protein, 60% sequence similarity to CCL3
CCL5 (RANTES) - Heavily upregulated durring viral infection
CCL7 (MCP-3) - Recruites monocyte lineages to sites of inflamation
CCL8 (MCP-2) - Aids in promoting chemotaxis in myeloid cells
Chemokine Receptors
CRP (C-Reavtive Protein) - an indicator of stress
CXCL12 (SDF-1) - Involved in embryogenisis, haematopoesis, and immune function
EGF (Epidermal Growth Factor) - Proliferation of mesenchyman and epithelial cells
Eotaxin (CCL11) - Pro-inflamitory and imunomodulatory
EPO (Erythropoietin) - Stimulates red blood cell proliferation
IFNy - Interferon, a growing cytokine family
IL-1 - Interleukin 1, a proinflammitory cytokine
IL-2 - A strong mediator of the immune resoponse in many cell types
IL-3 - Stimulates proliferation of pluripotent hematopoietic stem cells
IL-4 - Acts as a strong immuno-modulatory promotor
IL-5 - Associated with growth and differentiation of B-cells and eosinophils
IL-6 - Multifunctional protein involved with most immunological processes
IL-12 - Acts as a chemoattractant for macrophages
IL-15 - Similar to IL-2, stimulates T-cell and B-cell proliferation
IL-17 - A mediator of communication in the immune system
IL-18 - Pro-inflammatory cytokine
IL-23 - Has similar active sites to IL-12
IL-32 - Pro-inflammatory cytokine
JAK - Family of tyrosine kinases involved in membrane bound receptor signals
JE - see CCL2
Lactoferrin - Glycoprotein also known as transferrin
Leptin - Produced by adipocytes, required for control of bodyweight
MDA-7 - Member of the IL-10 family
MCP-1 - Monocyte chemotactic and activating factor, see CCL2
MIC-1 - Macrophage inhibitory cytokine-1
MIP-1a - Macrophage inflammatory protein 1 alpha
MIP-1b - Macrophage inflammatory protein 1 alpha
P38-MAPK - Mitogen-activated protein kinase (MAPK)
PDGF - Platelet derived growth factor
SOCS - Suppressors of cytokine signaling (SOCS)
TGF-b - Transforming growth factor beta
TNFa - Tumor necrosis factor alpha
TRAIL - (TNF)-related apoptosis inducing ligand
